Academic sites for research on controlled release systems

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Robert Langer, MIT

Nicholas Peppas, Purdue

Jindrich Kopecek, Utah

Jeffrey Hubbell, ETH and UNI Zürich

Mark Saltzman, Cornell

Kam Leong, Johns Hopkins

Paolo Colombo, Universeta Degli Studi Di Parma, Italy

Abraham Domb, Israel

Harold Hopfenberg, North Carolina

Rafael Ottenbrite, VCU

Garnet Peck, Purdue

Kinam Park, Purdue

Rita Nicholov, Toronto

Y-L. Cheng, Toronto

Helen Burt, British Columbia

UCSF, Drug Delivery Group

Biomaterials Research Groups

The high-value application of biodegradable/bioabsorbable polymers in the field
of drug delivery, has led to the patenting of many of the existing as well
as newly developed biomedical polymers such as polyanhydrides and poly-
phosphoesters. Thus efforts have intensified towards development of new
patentable polymers which can be used in the field of biomedicine. Such a
product development includes various steps briefly outlined herein:

Synthesis of a novel polymer which has a structure that is unique enough to be patented
Studying the degradation characteristics of this polymer (whether it degrades in a reasonable time period as required by its application; whether the degradation profile is controllable/predictable).
Study the degradation products (whether such products are bioabsorbable or toxic).
Study the drug release profiles, drug-polymer interactions, stability of the drug in the polymer etc.
Carry out clinical tests in animals to study the drug release and polymer degradation in vivo.

I am presently developing a page which examines the development of such
biomaterials, starting with a look at different research groups involved in
the development of such materials. You are welcome to take a look at Biomaterials Research Groups

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